Gangrene Research Today is a free monthly online journal that collates and summarizes the latest research about Gangrene, including details on smoking, treatment, causes, amputation, necrosis. | ||||||
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Gas gangrene and osteomyelitis of the foot in a diabetic patient treated with tea tree oil.Cooney DR, Cooney NL Department of Emergency Medicine, Division of Hyperbaric Medicine, SUNY Upstate Medical University, EMSTAT Center/550 East Genesee, Syracuse, New York 13202, USA. Diabetic foot wounds represent a class of chronic non-healing wounds that can lead to the development of soft tissue infections and osteomyelitis. We reviewed the case of a 44-year-old female with a diabetic foot wound who developed gas gangrene while treating her wound with tea tree oil, a naturally derived antibiotic agent. This case report includes images that represent clinical examination and x-ray findings of a patient who required broad-spectrum antibiotics and emergent surgical consultation. Emergency Department (ED) detection of these complications may prevent loss of life or limb in these patients. Published 11 May 2011 in Int J Emerg Med, 4: 14. Articles on Gangrene published 9 May 2011: Hyperbaric oxygen therapy adjunctive to surgical debridement in management of Fournier's gangrene: usefulness of a severity index score in predicting disease gravity and patient survival. Actas Urol Esp, 35(6): 332-338. INTRODUCTION: Hyperbaric oxygen therapy (HBOT) concomitant to surgery has been reported to reduce Fournier's gangrene (FG) mortality compared to exclusive surgical debridement. Most report from centers with relatively few patients using only surgical procedure. To assess efficiency of aggressive debridement with adjunctive HBOT. To evaluate Fournier's gangrene severity score index (FGSI) predictive value. MATERIAL AND METHODS: 70 Fournier's gangrene (FG) treated by surgical debridement and ... [Abstract] [Full-text] Articles on Gangrene published 4 May 2011: Peripheral Gangrene in a Breast Fed Neonate-Is Hypernatremic Dehydration the Cause? Indian J Pediatr. Hypernatremic dehydration in breast fed neonates is a rare but increasingly recognized problem. If not identified early, it may lead to potentially life threatening complications. The authors describe a neonate who developed thrombosis and lower limb ischemia secondary to hypernatremic dehydration. Peripheral gangrene, as a result of hypernatremic dehydration is extremely uncommon and has rarely been reported before. [Abstract] [Full-text] Articles on Gangrene published 2 May 2011: Twenty Years of Experience in the Treatment of Spontaneous Aorto-venous Fistulas in a Developing Country. World J Surg. BACKGROUND: One of the rare forms of abdominal aortic aneurysm (AAA) rupture is the rupture into great abdominal veins such as the inferior vein cava (IVC), the iliac veins, or the left renal vein, with the formation of direct or indirect aorto-caval fistula (ACF). The purpose of the present study was to summarize 20 years of experience at a single referral center for vascular surgery in a developing country, and to discuss the clinical presentation, diagnosis, treatment options, and outcome ... [Abstract] [Full-text] Articles on Gangrene published 26 April 2011: Risk Factors for Intestinal Gangrene in Children with Small Bowel Volvulus. J Pediatr Gastroenterol Nutr. OBJECTIVES:: Pediatric small bowel volvulus (SBV) is a surgical emergency, and early diagnosis is difficult. We analyzed the clinical manifestations, imaging findings, and laboratory parameters in children with SBV and attempted to determine the risk factors for bowel gangrene. METHODS:: Forty-nine children (35 males and 14 females) with SBV who were admitted to the hospital over 13 years were enrolled. Clinical and laboratory parameters and evaluation measures included fever, abdominal pain, ... [Abstract] [Full-text] Risk Factors for Intestinal Gangrene in Children with Small Bowel Volvulus. J Pediatr Gastroenterol Nutr. OBJECTIVES:: Pediatric small bowel volvulus (SBV) is a surgical emergency, and early diagnosis is difficult. We analyzed the clinical manifestations, imaging findings, and laboratory parameters in children with SBV and attempted to determine the risk factors for bowel gangrene. METHODS:: Forty-nine children (35 males and 14 females) with SBV who were admitted to the hospital over 13 years were enrolled. Clinical and laboratory parameters and evaluation measures included fever, abdominal pain, ... [Abstract] [Full-text] Articles on Gangrene published 25 April 2011: Outcome of Midfoot Amputations in Diabetic Gangrene. Ann Vasc Surg. BACKGROUND: Persistent high incidence of limb loss resulting from advanced foot gangrene in patients with diabetes prompted an aggressive foot salvage surgery as a final attempt before below-the-knee amputation (BKA). The aim of this study was to evaluate the role of transtarsal amputations in achieving limb salvage at our vascular surgery unit, King Fahd Hospital of the University, Saudi Arabia. METHODS: A prospective study was performed on all patients with diabetes who were admitted to the ... [Abstract] [Full-text] Inositol Hexakisphosphate-dependent Processing of Clostridium sordellii Lethal Toxin and Clostridium novyi {alpha}-Toxin. J Biol Chem, 286(17): 14779-86. Clostridium sordellii lethal toxin and Clostridium novyi α-toxin, which are virulence factors involved in the toxic shock and gas gangrene syndromes, are members of the family of clostridial glucosylating toxins. The toxins inactivate Rho/Ras proteins by glucosylation or attachment of GlcNAc (α-toxin). Here, we studied the activation of the autoproteolytic processing of the toxins by inositol hexakisphosphate (InsP(6)) and compared it with the processing of Clostridium difficile toxin B. In ... [Abstract] [Full-text] Outcome of Midfoot Amputations in Diabetic Gangrene. Ann Vasc Surg. BACKGROUND: Persistent high incidence of limb loss resulting from advanced foot gangrene in patients with diabetes prompted an aggressive foot salvage surgery as a final attempt before below-the-knee amputation (BKA). The aim of this study was to evaluate the role of transtarsal amputations in achieving limb salvage at our vascular surgery unit, King Fahd Hospital of the University, Saudi Arabia. METHODS: A prospective study was performed on all patients with diabetes who were admitted to the ... [Abstract] [Full-text] © 2005-2011 Gangrene Research Today. All Rights Reserved. |
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