Gangrene Research - Smoking, Treatment, Causes, Amputation, Necrosis

Gangrene Research Today is a free monthly online journal that collates and summarizes the latest research about Gangrene, including details on smoking, treatment, causes, amputation, necrosis.


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Intrauterine gangrene of the lower extremity in the newborn: a report of two cases.

Nagai MK, Littleton AG, Gabos PG

Department of Orthopaedic Surgery, Alfred I. duPont Hospital for Children, Wilmington, DE 19803, USA.

We describe 2 cases of intrauterine gangrene involving the lower extremity in 2 unrelated neonates. Both cases were complicated by prematurity, and 1 case was complicated by an intrauterine distal femur fracture and twin-twin transfusion syndrome. Both cases resulted in profound ischemic necrosis from the knee to the foot, requiring knee disarticulation. In both cases, a follow-up period of 7 years is now completed, and no further medical or surgical complications have arisen.

Published 22 June 2007 in J Pediatr Orthop, 27(5): 499-503.
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